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Mechanosensitive Rap1 activation promotes barrier function of lung vascular endothelium under cyclic stretch
Mechanical ventilation remains an imperative treatment for the patients with acute respiratory distress syndrome, but can also exacerbate lung injury. We have previously described a key role of RhoA GTPase in high cyclic stretch (CS)–induced endothelial cell (EC) barrier dysfunction. However, cellul...
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| Vydáno v: | Mol Biol Cell |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589902/ https://ncbi.nlm.nih.gov/pubmed/30759056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-07-0422 |
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