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Mechanosensitive Rap1 activation promotes barrier function of lung vascular endothelium under cyclic stretch
Mechanical ventilation remains an imperative treatment for the patients with acute respiratory distress syndrome, but can also exacerbate lung injury. We have previously described a key role of RhoA GTPase in high cyclic stretch (CS)–induced endothelial cell (EC) barrier dysfunction. However, cellul...
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| 出版年: | Mol Biol Cell |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589902/ https://ncbi.nlm.nih.gov/pubmed/30759056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-07-0422 |
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