Enhancing the Ligand Efficiency of Anti-HIV Compounds Targeting Frameshift-Stimulating RNA

Ribosomal frameshifting, a process whereby a translating ribosome is diverted from one reading frame to another on a contiguous mRNA, is an important regulatory mechanism in biology and an opportunity for therapeutic intervention in several human diseases. In HIV, ribosomal frameshifting controls th...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem
Main Authors: Anokhina, Viktoriya S., McAnany, John D., Ciesla, Jessica H., Hilimire, Thomas A., Santoso, Netty, Miao, Hongyu, Miller, Benjamin L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589821/
https://ncbi.nlm.nih.gov/pubmed/31101492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.05.009
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