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Enhancing the Ligand Efficiency of Anti-HIV Compounds Targeting Frameshift-Stimulating RNA
Ribosomal frameshifting, a process whereby a translating ribosome is diverted from one reading frame to another on a contiguous mRNA, is an important regulatory mechanism in biology and an opportunity for therapeutic intervention in several human diseases. In HIV, ribosomal frameshifting controls th...
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| Udgivet i: | Bioorg Med Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589821/ https://ncbi.nlm.nih.gov/pubmed/31101492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.05.009 |
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