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Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides
Evidence is presented that morpholino, 2′-O-methyl, phosphorothioate, and RNA antisense oligonucleotides can direct site-specific -1 translational frameshifting when annealed to mRNA downstream from sequences where the P- and A-site tRNAs are both capable of repairing with -1 frame codons. The effic...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Copyright 2004 by RNA Society
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370650/ https://ncbi.nlm.nih.gov/pubmed/15383681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7810204 |
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