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Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides

Evidence is presented that morpholino, 2′-O-methyl, phosphorothioate, and RNA antisense oligonucleotides can direct site-specific -1 translational frameshifting when annealed to mRNA downstream from sequences where the P- and A-site tRNAs are both capable of repairing with -1 frame codons. The effic...

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Bibliografski detalji
Glavni autori: HOWARD, MICHAEL T., GESTELAND, RAYMOND F., ATKINS, JOHN F.
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2004 by RNA Society 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370650/
https://ncbi.nlm.nih.gov/pubmed/15383681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7810204
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