Short-duration hyperoxia causes genotoxicity in mouse lungs: protection by volatile anesthetic isoflurane

High concentrations of oxygen (hyperoxia) are routinely used during anesthesia, and supplemental oxygen is also administered in connection with several other clinical conditions. Although prolonged hyperoxia is known to cause acute lung injury (ALI), whether short-duration hyperoxia causes lung toxi...

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Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Kundumani-Sridharan, Venkatesh, Subramani, Jaganathan, Raghavan, Somasundaram, Maiti, Guru P., Owens, Cade, Walker, Trevor, Wasnick, John, Idell, Steven, Das, Kumuda C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589579/
https://ncbi.nlm.nih.gov/pubmed/30810065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00142.2018
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