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Thioredoxin Uses a GSH-independent Route to Deglutathionylate Endothelial Nitric-oxide Synthase and Protect against Myocardial Infarction

Reversible glutathionylation plays a critical role in protecting protein function under conditions of oxidative stress generally and for endothelial nitric-oxide synthase (eNOS) specifically. Glutathione-dependent glutaredoxin-mediated deglutathionylation of eNOS has been shown to confer protection...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Subramani, Jaganathan, Kundumani-Sridharan, Venkatesh, Hilgers, Rob H. P., Owens, Cade, Das, Kumuda C.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095395/
https://ncbi.nlm.nih.gov/pubmed/27587398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745034
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