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Thioredoxin decreases anthracycline cardiotoxicity, but sensitizes cancer cell apoptosis

Cardiotoxicity is a major limitation for anthracycline chemotherapy although anthracyclines are potent antitumor agents. The precise mechanism underlying clinical heart failure due to anthracycline treatment is not fully understood, but is believed to be due, in part, to lipid peroxidation and the g...

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Bibliografische gegevens
Gepubliceerd in:Cardiovasc Toxicol
Hoofdauteurs: Das, Kumuda C., Muniyappa, Harish, Kundumani-Sridharan, Venkatesh, Subramani, Jaganathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854973/
https://ncbi.nlm.nih.gov/pubmed/32880787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12012-020-09605-2
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