Short-duration hyperoxia causes genotoxicity in mouse lungs: protection by volatile anesthetic isoflurane

High concentrations of oxygen (hyperoxia) are routinely used during anesthesia, and supplemental oxygen is also administered in connection with several other clinical conditions. Although prolonged hyperoxia is known to cause acute lung injury (ALI), whether short-duration hyperoxia causes lung toxi...

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Gepubliceerd in:Am J Physiol Lung Cell Mol Physiol
Hoofdauteurs: Kundumani-Sridharan, Venkatesh, Subramani, Jaganathan, Raghavan, Somasundaram, Maiti, Guru P., Owens, Cade, Walker, Trevor, Wasnick, John, Idell, Steven, Das, Kumuda C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589579/
https://ncbi.nlm.nih.gov/pubmed/30810065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00142.2018
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