Conditioning of Myoblast Secretome using Mesenchymal Stem/Stromal Cell Spheroids Improves Bone Repair

Local muscle loss associated with open fractures remains an obstacle to functional recovery and bone healing. Muscle cells secrete bioactive myokines that elicit autocrine and paracrine effects and initiate signaling pathways for regenerating damaged muscle and bone. Mesenchymal stem/stromal cells (...

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Bibliographic Details
Published in:Bone
Main Authors: Saiz, Augustine M., Gionet-Gonzales, Marissa, Lee, Mark A., Leach, J. Kent
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589400/
https://ncbi.nlm.nih.gov/pubmed/31102712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.05.018
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