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Conditioning of Myoblast Secretome using Mesenchymal Stem/Stromal Cell Spheroids Improves Bone Repair

Local muscle loss associated with open fractures remains an obstacle to functional recovery and bone healing. Muscle cells secrete bioactive myokines that elicit autocrine and paracrine effects and initiate signaling pathways for regenerating damaged muscle and bone. Mesenchymal stem/stromal cells (...

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Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Saiz, Augustine M., Gionet-Gonzales, Marissa, Lee, Mark A., Leach, J. Kent
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589400/
https://ncbi.nlm.nih.gov/pubmed/31102712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.05.018
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