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UTX Mutations in Human Cancer
Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX, encoded by KDM6A) is a histone demethylase that targets di- and tri-methylated histone H3 lysine 27 (H3K27). UTX function has been linked to homeotic gene expression, embryonic development, and cellular reprogramming. UTX and it...
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| Publié dans: | Cancer Cell |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589339/ https://ncbi.nlm.nih.gov/pubmed/30753822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.01.001 |
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