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Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche

Adult stem cells reside in microenvironments called niches, where they are regulated by both extrinsic cues, such as signaling from neighboring cells, and intrinsic factors, such as chromatin structure. Here we report that in the Drosophila testis niche an H3K27me3-specific histone demethylase encod...

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Autori principali: Tarayrah, Lama, Herz, Hans-Martin, Shilatifard, Ali, Chen, Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583039/
https://ncbi.nlm.nih.gov/pubmed/23364332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.089433
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