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UTX Mutations in Human Cancer

Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX, encoded by KDM6A) is a histone demethylase that targets di- and tri-methylated histone H3 lysine 27 (H3K27). UTX function has been linked to homeotic gene expression, embryonic development, and cellular reprogramming. UTX and it...

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Bibliografiske detaljer
Udgivet i:Cancer Cell
Main Authors: Wang, Lu, Shilatifard, Ali
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589339/
https://ncbi.nlm.nih.gov/pubmed/30753822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.01.001
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