GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer

GATA3 has emerged as a prominent transcription factor required for maintaining mammary-gland homeostasis. GATA3 loss is associated with aggressive breast cancer development, but the mechanism by which breast cancer is affected by the loss of GATA3 function remains unclear. Here, we report that GATA3...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Yu, Wenqian, Huang, Wei, Yang, Yang, Qiu, Rongfang, Zeng, Yi, Hou, Yongqiang, Sun, Gancheng, Shi, Hang, Leng, Shuai, Feng, Dandan, Chen, Yang, Wang, Shuang, Teng, Xu, Yu, Hefen, Wang, Yan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828764/
https://ncbi.nlm.nih.gov/pubmed/31685800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2062-7
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