The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex

The homeodomain transcription factor SIX3 was recently reported to be a negative regulator of the Wnt pathway and has an emerging role in cancer. However, how SIX3 contributes to tumorigenesis and metastasis is poorly understood. Methods: We employed affinity purification and mass spectrometry (MS)...

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Publicado en:Theranostics
Autores principales: Zheng, Yu, Zeng, Yi, Qiu, Rongfang, Liu, Ruiqiong, Huang, Wei, Hou, Yongqiang, Wang, Shuang, Leng, Shuai, Feng, Dandan, Yang, Yang, Wang, Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2018
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817105/
https://ncbi.nlm.nih.gov/pubmed/29463994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.22328
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