טוען...
Activation of the mGlu(1) metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M(4) muscarinic receptor allosteric modulators
Recent clinical and preclinical studies suggest that selective activators of the M(4) muscarinic acetylcholine receptor have potential as a novel treatment for schizophrenia. M(4) activation inhibits striatal dopamine release by mobilizing endocannabinoids, providing a mechanism for local effects on...
שמור ב:
| הוצא לאור ב: | Mol Psychiatry |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588501/ https://ncbi.nlm.nih.gov/pubmed/30116027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0206-2 |
| תגים: |
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