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Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal

Impairment of mitochondrial transport has long been implicated in the pathogenesis of neuropathy and neurodegeneration. However, the role of mitochondria in stabilizing motor nerve terminals at neuromuscular junction (NMJ) remains unclear. We previously demonstrated that mice lacking the antioxidant...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Neurol
Prif Awduron: Hayes, Lindsey R., Asress, Seneshaw A., Li, Yingjie, Galkin, Alexander, Stepanova, Anna, Kawamata, Hibiki, Manfredi, Giovanni, Glass, Jonathan D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588488/
https://ncbi.nlm.nih.gov/pubmed/31082391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.05.008
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