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Absence of SOD1 leads to oxidative stress in peripheral nerve and causes a progressive distal motor axonopathy

Oxidative stress is commonly implicated in the pathogenesis of motor neuron disease. However, the cause and effect relationship between oxidative stress and motor neuron degeneration is poorly defined. We recently identified denervation at the neuromuscular junction in mice lacking the antioxidant e...

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Detaylı Bibliyografya
Asıl Yazarlar: Fischer, Lindsey R., Li, Yingjie, Asress, Seneshaw A., Jones, Dean P., Glass, Jonathan D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068963/
https://ncbi.nlm.nih.gov/pubmed/21963651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.09.020
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