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Distal axonopathy with structural persistence in glaucomatous neurodegeneration

An early hallmark of neuronal degeneration is distal transport loss and axon pathology. Glaucoma involves the degeneration of retinal ganglion cell (RGC) neurons and their axons in the optic nerve. Here we show that, like other neurodegenerations, distal axon injury appears early in mouse glaucoma....

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Bibliografiske detaljer
Main Authors: Crish, Samuel D., Sappington, Rebecca M., Inman, Denise M., Horner, Philip J., Calkins, David J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841892/
https://ncbi.nlm.nih.gov/pubmed/20194762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913141107
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