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Proximal Inhibition of p38 MAPK Stress Signaling Prevents Distal Axonopathy
The p38 mitogen-activated protein kinase (MAPK) isoforms are phosphorylated by a variety of stress stimuli in neurodegenerative disease and act as upstream activators of myriad pathogenic processes. Thus, p38 MAPK inhibitors are of growing interest as possible therapeutic interventions. Axonal dysfu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775981/ https://ncbi.nlm.nih.gov/pubmed/23859799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.07.001 |
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