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Genetic Suppression of IKK2/NF-κB in Astrocytes Inhibits Neuroinflammation and Reduces Neuronal Loss in the MPTP-Probenecid Model of Parkinson’s Disease
Neuroinflammatory activation of glia is considered a pathological hallmark of Parkinson’s disease (PD) and is seen in both human PD patients and in animal models of PD; however, the relative contributions of these cell types, especially astrocytes, to the progression of disease is not fully understo...
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| Publicat a: | Neurobiol Dis |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588478/ https://ncbi.nlm.nih.gov/pubmed/30818064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.02.020 |
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