NF-κB Signaling in Astrocytes Modulates Brain Inflammation and Neuronal Injury Following Sequential Exposure to Manganese and MPTP During Development and Aging

Chronic exposure to manganese (Mn) is associated with neuroinflammation and extrapyramidal motor deficits resembling features of Parkinson’s disease. Activation of astrocytes and microglia is implicated in neuronal injury from Mn but it is not known whether early life exposure to Mn may predispose g...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Hammond, Sean L, Bantle, Collin M, Popichak, Katriana A, Wright, Katie A, Thompson, Delaney, Forero, Catalina, Kirkley, Kelly S, Damale, Pranav U, Chong, Edwin K P, Tjalkens, Ronald B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Neurotoxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548288/
https://ncbi.nlm.nih.gov/pubmed/32692843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados