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Differential Peroxiredoxin Hyperoxidation Regulates MAP Kinase Signaling in Human Articular Chondrocytes
The peroxiredoxin (Prx) family of Cys-dependent peroxidases control intracellular levels of H(2)O(2) and can regulate signal transduction. Inhibition of the Prxs, through hyperoxidation amongst other mechanisms, leads to oxidative stress conditions that can alter homeostatic signaling. To determine...
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| Published in: | Free Radic Biol Med |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588440/ https://ncbi.nlm.nih.gov/pubmed/30639614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.01.005 |
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