Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins

2-Cys peroxiredoxins (Prxs) modulate hydrogen peroxide (H(2)O(2))-mediated cell signaling. At high H(2)O(2) levels, eukaryotic Prxs can be inactivated by hyperoxidation and are classified as sensitive Prxs. In contrast, prokaryotic Prxs are categorized as being resistant to hyperoxidation and lack t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Bolduc, Jesalyn A., Nelson, Kimberly J., Haynes, Alexina C., Lee, Jingyun, Reisz, Julie A., Graff, Aaron H., Clodfelter, Jill E., Parsonage, Derek, Poole, Leslie B., Furdui, Cristina M., Lowther, W. Todd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Enzymology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066324/
https://ncbi.nlm.nih.gov/pubmed/29884768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001690
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