H(2)O(2) oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes

Reactive oxygen species (ROS), in particular H(2)O(2), regulate intracellular signaling through reversible oxidation of reactive protein thiols present in a number of kinases and phosphatases. H(2)O(2) has been shown to regulate mitogen-activated protein kinase (MAPK) signaling depending on the cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Nelson, Kimberly J., Bolduc, Jesalyn A., Wu, Hanzhi, Collins, John A., Burke, Elizabeth A., Reisz, Julie A., Klomsiri, Chananat, Wood, Scott T., Yammani, Raghunatha R., Poole, Leslie B., Furdui, Cristina M., Loeser, Richard F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200941/
https://ncbi.nlm.nih.gov/pubmed/30190325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004613
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