H(2)O(2) oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes

Reactive oxygen species (ROS), in particular H(2)O(2), regulate intracellular signaling through reversible oxidation of reactive protein thiols present in a number of kinases and phosphatases. H(2)O(2) has been shown to regulate mitogen-activated protein kinase (MAPK) signaling depending on the cell...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nelson, Kimberly J., Bolduc, Jesalyn A., Wu, Hanzhi, Collins, John A., Burke, Elizabeth A., Reisz, Julie A., Klomsiri, Chananat, Wood, Scott T., Yammani, Raghunatha R., Poole, Leslie B., Furdui, Cristina M., Loeser, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200941/
https://ncbi.nlm.nih.gov/pubmed/30190325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004613
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