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Interleukin-7 Stimulates Secretion of S100A4 by Activating the JAK-STAT Signaling Pathway in Human Articular Chondrocytes
OBJECTIVE: S100A4 has been shown to be increased in OA cartilage and to stimulate chondrocytes to produce MMP-13 through activation of the receptor for advanced glycation end products (RAGE). The aim of this study was to understand the mechanism of S100A4 secretion by chondrocytes. METHODS: Human ar...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676111/ https://ncbi.nlm.nih.gov/pubmed/19248116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24295 |
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