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Interleukin-7 Stimulates Secretion of S100A4 by Activating the JAK-STAT Signaling Pathway in Human Articular Chondrocytes

OBJECTIVE: S100A4 has been shown to be increased in OA cartilage and to stimulate chondrocytes to produce MMP-13 through activation of the receptor for advanced glycation end products (RAGE). The aim of this study was to understand the mechanism of S100A4 secretion by chondrocytes. METHODS: Human ar...

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Detalhes bibliográficos
Main Authors: Yammani, Raghunatha R., Long, David, Loeser, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676111/
https://ncbi.nlm.nih.gov/pubmed/19248116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24295
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