Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain

Transgenic Tg2576 mice expressing human amyloid precursor protein (hAPP) with the Swedish mutation are among the most frequently used animal models to study the amyloid pathology related to Alzheimer's disease (AD). The transgene expression in this model is considered to be neuron‐specific. Usi...

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Udgivet i:Glia
Main Authors: Heiland, Tina, Zeitschel, Ulrike, Puchades, Maja A., Kuhn, Peer‐Hendrik, Lichtenthaler, Stefan F., Bjaalie, Jan G., Hartlage‐Rübsamen, Maike, Roßner, Steffen, Höfling, Corinna
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588085/
https://ncbi.nlm.nih.gov/pubmed/30485540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23550
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