Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models

Patient‐derived xenograft (PDX) models have become an important asset in translational cancer research. However, to provide a robust preclinical platform, PDXs need to accommodate the tumor heterogeneity that is observed in patients. Colorectal cancer (CRC) can be stratified into four consensus mole...

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Udgivet i:Int J Cancer
Main Authors: Prasetyanti, Pramudita R., van Hooff, Sander R., van Herwaarden, Tessa, de Vries, Nathalie, Kalloe, Kieshen, Rodermond, Hans, van Leersum, Ronald, de Jong, Joan H., Franitza, Marek, Nürnberg, Peter, Todaro, Matilde, Stassi, Giorgio, Medema, Jan Paul
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Tumor Markers and Signatures
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587871/
https://ncbi.nlm.nih.gov/pubmed/30151914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31767
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