Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models

Patient‐derived xenograft (PDX) models have become an important asset in translational cancer research. However, to provide a robust preclinical platform, PDXs need to accommodate the tumor heterogeneity that is observed in patients. Colorectal cancer (CRC) can be stratified into four consensus mole...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Prasetyanti, Pramudita R., van Hooff, Sander R., van Herwaarden, Tessa, de Vries, Nathalie, Kalloe, Kieshen, Rodermond, Hans, van Leersum, Ronald, de Jong, Joan H., Franitza, Marek, Nürnberg, Peter, Todaro, Matilde, Stassi, Giorgio, Medema, Jan Paul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Tumor Markers and Signatures
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587871/
https://ncbi.nlm.nih.gov/pubmed/30151914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31767
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