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Patient-derived xenograft (PDX) models, applications and challenges in cancer research

Abstract The establishing of the first cancer models created a new perspective on the identification and evaluation of new anti-cancer therapies in preclinical studies. Patient-derived xenograft models are created by tumor tissue engraftment. These models accurately represent the biology and heterog...

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Detalhes bibliográficos
Main Authors: Shahrokh Abdolahi, Zeinab Ghazvinian, Samad Muhammadnejad, Mahshid Saleh, Hamid Asadzadeh Aghdaei, Kaveh Baghaei
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Journal of Translational Medicine
Assuntos:
PDX
Acesso em linha:https://doi.org/10.1186/s12967-022-03405-8
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