Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation

A stochastic approach of copurification of the protease Cathepsin L that results in product fragmentation during purification processing and storage is presented. Cathepsin L was identified using mass spectroscopy, characterization of proteolytic activity, and comparison with fragmentation patterns...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biotechnol Prog
Principais autores: Luo, Haibin, Tie, Liu, Cao, Mingyan, Hunter, Alan K., Pabst, Timothy M., Du, Jiali, Field, Raymond, Li, Yuling, Wang, William K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
RESEARCH ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587562/
https://ncbi.nlm.nih.gov/pubmed/30320962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.2732
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados