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Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X

The maturation status of dendritic cells (DCs) is crucial for effective antigen presentation and initiation of the primary immune response. Maturation stimuli cause the adhesion of immature DCs to the extracellular matrix, which is accompanied by recruitment of the CD11b/CD18 [macrophage antigen-1 (...

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Detalhes bibliográficos
Main Authors: Obermajer, Nataša, Švajger, Urban, Bogyo, Mathew, Jeras, Matjaž, Kos, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252843/
https://ncbi.nlm.nih.gov/pubmed/18701767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0508285
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