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Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X

The maturation status of dendritic cells (DCs) is crucial for effective antigen presentation and initiation of the primary immune response. Maturation stimuli cause the adhesion of immature DCs to the extracellular matrix, which is accompanied by recruitment of the CD11b/CD18 [macrophage antigen-1 (...

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Bibliografiska uppgifter
Huvudupphovsmän: Obermajer, Nataša, Švajger, Urban, Bogyo, Mathew, Jeras, Matjaž, Kos, Janko
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Society for Leukocyte Biology 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252843/
https://ncbi.nlm.nih.gov/pubmed/18701767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0508285
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