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Phosphoinositide 3‐kinase δ is a regulatory T‐cell target in cancer immunotherapy

Tumour infiltration by regulatory T (Treg) cells contributes to suppression of the anti‐tumour immune response, which limits the efficacy of immune‐mediated cancer therapies. The phosphoinositide 3‐kinase (PI3K) pathway has key roles in mediating the function of many immune cell subsets, including T...

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Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Lim, Ee Lyn, Okkenhaug, Klaus
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587315/
https://ncbi.nlm.nih.gov/pubmed/31107985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13082
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