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Phosphoinositide 3‐kinase δ is a regulatory T‐cell target in cancer immunotherapy

Tumour infiltration by regulatory T (Treg) cells contributes to suppression of the anti‐tumour immune response, which limits the efficacy of immune‐mediated cancer therapies. The phosphoinositide 3‐kinase (PI3K) pathway has key roles in mediating the function of many immune cell subsets, including T...

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Detalles Bibliográficos
Publicado en:Immunology
Main Authors: Lim, Ee Lyn, Okkenhaug, Klaus
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587315/
https://ncbi.nlm.nih.gov/pubmed/31107985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13082
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