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Phosphoinositide 3‐kinase δ is a regulatory T‐cell target in cancer immunotherapy

Tumour infiltration by regulatory T (Treg) cells contributes to suppression of the anti‐tumour immune response, which limits the efficacy of immune‐mediated cancer therapies. The phosphoinositide 3‐kinase (PI3K) pathway has key roles in mediating the function of many immune cell subsets, including T...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Lim, Ee Lyn, Okkenhaug, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587315/
https://ncbi.nlm.nih.gov/pubmed/31107985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13082
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