Retinoic acid and 6-formylindolo(3,2–b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML

In non-APL AML, identification of a signaling signature would predict potentially actionable targets to enhance differentiation effects of all-trans-retinoic acid (RA) and make combination differentiation therapy realizable. Components of such a signaling machine/signalsome found to drive RA-induced...

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Veröffentlicht in:Leuk Lymphoma
Hauptverfasser: Bunaciu, Rodica P., MacDonald, Robert J., Jensen, Holly A., Gao, Feng, Wang, Xin, Johnson, Lynn, Varner, Jeffrey D., Yen, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586535/
https://ncbi.nlm.nih.gov/pubmed/30570341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2018.1543880
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