Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

Acute myeloid leukemia (AML) has high mortality rates, perhaps reflecting a lack of understanding of the molecular diversity in various subtypes and a lack of known actionable targets. There are currently 12 open clinical trials for AML using combination therapeutic modalities including all-trans re...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Bunaciu, Rodica P., MacDonald, Robert J., Gao, Feng, Johnson, Lynn M., Varner, Jeffrey D., Wang, Xin, Nataraj, Sarah, Guzman, Monica L., Yen, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790527/
https://ncbi.nlm.nih.gov/pubmed/29423110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23642
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