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Ligand-Enabled, Palladium-Catalyzed β-C(sp(3))–H Arylation of Weinreb Amides

We report the development of Pd(II)-catalyzed C(sp(3))–H arylation of Weinreb amides. This work demonstrates the first example of using Weinreb amide as a directing group for transition metal-catalyzed C(sp(3))–H activation. Both the inductive effect and the potential bidentate coordination mode of...

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Bibliografiske detaljer
Udgivet i:ACS Catal
Main Authors: Park, Hojoon, Chekshin, Nikita, Shen, Peng-Xiang, Yu, Jin-Quan
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586421/
https://ncbi.nlm.nih.gov/pubmed/31223513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.8b03014
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