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A General and Practical Palladium-Catalyzed Direct α-Arylation of Amides with Aryl Halides
An efficient system for the direct catalytic intermolecular α-arylation of acetamide derivatives with aryl bromides and chlorides is presented. The palladium catalyst is supported by Kwong’s indole-based phosphine ligand and provides monoarylated amides in up to 95% yield. Excellent chemoselectiviti...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3994175/ https://ncbi.nlm.nih.gov/pubmed/24765060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201300851 |
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