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A General and Practical Palladium-Catalyzed Direct α-Arylation of Amides with Aryl Halides

An efficient system for the direct catalytic intermolecular α-arylation of acetamide derivatives with aryl bromides and chlorides is presented. The palladium catalyst is supported by Kwong’s indole-based phosphine ligand and provides monoarylated amides in up to 95% yield. Excellent chemoselectiviti...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zheng, Bing, Jia, Tiezheng, Walsh, Patrick J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994175/
https://ncbi.nlm.nih.gov/pubmed/24765060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201300851
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