Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a lethal, muscle degenerative disease causing premature death of affected children. DMD is characterized by mutations in the dystrophin gene that result in a loss of the dystrophin protein. Loss of dystrophin causes an associated reduction in proteins of the dyst...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Fontelonga, Tatiana M, Jordan, Brennan, Nunes, Andreia M, Barraza-Flores, Pamela, Bolden, Nicholas, Wuebbles, Ryan D, Griner, Lesley Mathews, Hu, Xin, Ferrer, Marc, Marugan, Juan, Southall, Noel, Burkin, Dean J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
General Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586148/
https://ncbi.nlm.nih.gov/pubmed/30806670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz044
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