Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a devastating X-linked disease affecting ~1 in 5000 males. DMD patients exhibit progressive muscle degeneration and weakness, leading to loss of ambulation and premature death from cardiopulmonary failure. We previously reported that mouse Laminin-111 (msLam-111)...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Barraza-Flores, Pamela, Fontelonga, Tatiana M, Wuebbles, Ryan D, Hermann, Hailey J, Nunes, Andreia M, Kornegay, Joe N, Burkin, Dean J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
General Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687953/
https://ncbi.nlm.nih.gov/pubmed/31179490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz086
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