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Open‐Label, Dose‐Escalation, Phase 1 Study of Safety and Single and Multiple‐Dose Pharmacokinetics of Dichlorphenamide in Healthy Volunteers

Single‐and multiple‐dose pharmacokinetics and safety were investigated in this phase 1 study of dichlorphenamide, a carbonic anhydrase inhibitor approved in the United States for treatment of primary periodic paralysis. Dichlorphenamide was administered to 6 cohorts (n = 6 each) of healthy adults. C...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Autor principal: Cohen, Fredric
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585844/
https://ncbi.nlm.nih.gov/pubmed/29762909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.464
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