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Phase 1 Dose‐Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Tofacitinib in Japanese Healthy Volunteers

The aim of the study was to characterize the pharmacokinetics, safety, and tolerability of tofacitinib, an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in healthy Japanese volunteers, and to compare these outcomes with those of he...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Pharmacol Drug Dev
Prif Awduron: Miyoshi, So, Krishnaswami, Sriram, Toyoizumi, Shigeyuki, Nakamura, Hiroyuki, Zwillich, Samuel H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003739/
https://ncbi.nlm.nih.gov/pubmed/31713350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.741
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