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Phase 1 Dose‐Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Tofacitinib in Japanese Healthy Volunteers

The aim of the study was to characterize the pharmacokinetics, safety, and tolerability of tofacitinib, an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in healthy Japanese volunteers, and to compare these outcomes with those of he...

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Publicado en:Clin Pharmacol Drug Dev
Autores principales: Miyoshi, So, Krishnaswami, Sriram, Toyoizumi, Shigeyuki, Nakamura, Hiroyuki, Zwillich, Samuel H.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003739/
https://ncbi.nlm.nih.gov/pubmed/31713350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.741
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