Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

OBJECTIVES: Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune diseases characterised clinically by muscle weakness and heterogeneous systemic organ involvement. The strongest genetic risk is within the major histocompatibility complex (MHC). Since autoantibody presence defin...

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Détails bibliographiques
Publié dans:Ann Rheum Dis
Auteurs principaux: Rothwell, Simon, Chinoy, Hector, Lamb, Janine A, Miller, Frederick W, Rider, Lisa G, Wedderburn, Lucy R, McHugh, Neil J, Mammen, Andrew L, Betteridge, Zoe E, Tansley, Sarah L, Bowes, John, Vencovský, Jiří, Deakin, Claire T, Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M, Reed, Ann M, Molberg, Øyvind, Benveniste, Olivier, Mathiesen, Pernille R, Radstake, Timothy R D J, Doria, Andrea, de Bleecker, Jan, Lee, Annette T, Hanna, Michael G, Machado, Pedro M, Ollier, William E, Gregersen, Peter K, Padyukov, Leonid, O'Hanlon, Terrance P, Cooper, Robert G, Lundberg, Ingrid E
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2019
Sujets:
Myositis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585280/
https://ncbi.nlm.nih.gov/pubmed/31138531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-215046
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