Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

OBJECTIVES: Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune diseases characterised clinically by muscle weakness and heterogeneous systemic organ involvement. The strongest genetic risk is within the major histocompatibility complex (MHC). Since autoantibody presence defin...

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Veröffentlicht in:Ann Rheum Dis
Hauptverfasser: Rothwell, Simon, Chinoy, Hector, Lamb, Janine A, Miller, Frederick W, Rider, Lisa G, Wedderburn, Lucy R, McHugh, Neil J, Mammen, Andrew L, Betteridge, Zoe E, Tansley, Sarah L, Bowes, John, Vencovský, Jiří, Deakin, Claire T, Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M, Reed, Ann M, Molberg, Øyvind, Benveniste, Olivier, Mathiesen, Pernille R, Radstake, Timothy R D J, Doria, Andrea, de Bleecker, Jan, Lee, Annette T, Hanna, Michael G, Machado, Pedro M, Ollier, William E, Gregersen, Peter K, Padyukov, Leonid, O'Hanlon, Terrance P, Cooper, Robert G, Lundberg, Ingrid E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2019
Schlagworte:
Myositis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585280/
https://ncbi.nlm.nih.gov/pubmed/31138531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-215046
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