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Genome-wide Association Study Identifies HLA 8.1 Ancestral Haplotype Alleles as Major Genetic Risk Factors for Myositis Phenotypes

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic and environmental factors. To identify genetic risk factors in patients of European ancestry, we conducted a genome-wide association study (GWAS) of the major myositis phenotypes in a total of 1710 cas...

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Bibliografski detalji
Izdano u:Genes Immun
Glavni autori: Miller, Frederick W., Chen, Wei, O’Hanlon, Terrance P., Cooper, Robert G., Vencovsky, Jiri, Rider, Lisa G., Danko, Katalin, Wedderburn, Lucy R., Lundberg, Ingrid E., Pachman, Lauren M., Reed, Ann M., Ytterberg, Steven R., Padyukov, Leonid, Selva-O’Callaghan, Albert, Radstake, Timothy R., Isenberg, David A., Chinoy, Hector, Ollier, William E.R., Scheet, Paul, Peng, Bo, Lee, Annette, Byun, Jinyoung, Lamb, Janine A., Gregersen, Peter K., Amos, Christopher I.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840953/
https://ncbi.nlm.nih.gov/pubmed/26291516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.28
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