Genome-wide Association Study Identifies HLA 8.1 Ancestral Haplotype Alleles as Major Genetic Risk Factors for Myositis Phenotypes

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic and environmental factors. To identify genetic risk factors in patients of European ancestry, we conducted a genome-wide association study (GWAS) of the major myositis phenotypes in a total of 1710 cas...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Miller, Frederick W., Chen, Wei, O’Hanlon, Terrance P., Cooper, Robert G., Vencovsky, Jiri, Rider, Lisa G., Danko, Katalin, Wedderburn, Lucy R., Lundberg, Ingrid E., Pachman, Lauren M., Reed, Ann M., Ytterberg, Steven R., Padyukov, Leonid, Selva-O’Callaghan, Albert, Radstake, Timothy R., Isenberg, David A., Chinoy, Hector, Ollier, William E.R., Scheet, Paul, Peng, Bo, Lee, Annette, Byun, Jinyoung, Lamb, Janine A., Gregersen, Peter K., Amos, Christopher I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840953/
https://ncbi.nlm.nih.gov/pubmed/26291516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.28
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