Genome-wide Association Study Identifies HLA 8.1 Ancestral Haplotype Alleles as Major Genetic Risk Factors for Myositis Phenotypes

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic and environmental factors. To identify genetic risk factors in patients of European ancestry, we conducted a genome-wide association study (GWAS) of the major myositis phenotypes in a total of 1710 cas...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genes Immun
Hauptverfasser: Miller, Frederick W., Chen, Wei, O’Hanlon, Terrance P., Cooper, Robert G., Vencovsky, Jiri, Rider, Lisa G., Danko, Katalin, Wedderburn, Lucy R., Lundberg, Ingrid E., Pachman, Lauren M., Reed, Ann M., Ytterberg, Steven R., Padyukov, Leonid, Selva-O’Callaghan, Albert, Radstake, Timothy R., Isenberg, David A., Chinoy, Hector, Ollier, William E.R., Scheet, Paul, Peng, Bo, Lee, Annette, Byun, Jinyoung, Lamb, Janine A., Gregersen, Peter K., Amos, Christopher I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840953/
https://ncbi.nlm.nih.gov/pubmed/26291516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.28
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge