Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling

Receptor tyrosine kinase (RTK)-mediated hyperactivation of the MAPK/Erk pathway is responsible for a large number of pathogenic outcomes including many cancers. Considerable effort has been directed at targeting this pathway with varying degrees of long term therapeutic success. Under non-stimulated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Lin, Chi-Chuan, Suen, Kin Man, Stainthorp, Amy, Wieteska, Lukasz, Biggs, George S., Leitão, Andrei, Montanari, Carlos A., Ladbury, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Ireland 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584941/
https://ncbi.nlm.nih.gov/pubmed/31100409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.05.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados