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Isocitrate Dehydrogenase Mutations in Glioma: From Basic Discovery to Therapeutics Development

Isocitrate dehydrogenase (IDH) is a key rate-limiting enzyme in the Krebs cycle that plays an important role in energy metabolism. In recent years, it has been found that IDH mutations are closely related to the occurrence and development of glioma, and it is a notable potential therapeutic target....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Oncol
Päätekijät: Huang, Juan, Yu, Jialong, Tu, Lin, Huang, Nanqu, Li, Hang, Luo, Yong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584818/
https://ncbi.nlm.nih.gov/pubmed/31263678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00506
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